Are the Available DNA Sequence Alignments and Search Tools Reliable for Alu Research?

Sridhar Ramachandran

Abstract


The results of most bioinformatics and microbiology research studies that use SINEs depend entirely on the mechanism used to detect and count these element instances in the genome. Hence, the reliability and accuracy of the DNA sequence alignment and search tool is vital for genetic researches. This research report presents the findings from testing the reliability of some popular DNA Sequence alignment and search (SA&S) tools using a test/known genomic sequence. The findings reveal the need for novel tool design.

Keywords


Sequence Alignment; DNA Search tools; Alu polymorphism.

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References


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